AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within
(predicted: Human,Mouse,Rat,Dog,Cow,Sheep)
IHC-P,IHC-F,ICC/IF,ELISA,IF
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.